The Pfam:USP8_dimer domain within your query sequence starts at position 19 and ends at position 132, and its E-value is 3.9e-21.

HTDVSLSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKTDLLRKYNIE
Pfam:USP8_dimer

Pfam:USP8_dimer
Pfam domain

Pfam ACC: