The CDC48_N domain within your query sequence starts at position 44 and ends at position 135, and its E-value is 2.47e-1.
 CDC48_NCell division protein 48 (CDC48) N-terminal domain | |
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| SMART ACC: | SM001073 |
| Description: | This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases is a substrate 185-residue recognition domain (PUBMED:10531028). |
| InterPro ACC: | IPR003338 |
| InterPro abstract: | This entry represents the amino-terminal subdomain. The CDC48 N-terminal domain is a protein domain found in AAA ATPases including cell division protein 48 (CDC48), VCP-like ATPase (VAT) and N-ethylmaleimide sensitive fusion protein. It is a substrate recognition domain which binds polypeptides, prevents protein aggregation, and catalyses refolding of permissive substrates. It is composed … expand |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 6 871 CDC48_N domains in 6 866 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing CDC48_N domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing CDC48_N domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Metabolic |
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Relevant references for this domain
Primary literature for the CDC48_N domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a CDC48_N domain which could be assigned to a KEGG orthologous group, and not all proteins containing CDC48_N domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.