The POLAc domain within your query sequence starts at position 587 and ends at position 796, and its E-value is 2.6e-69.
All catalytic sites are present in this domain, and marked green in the sequence below. Check the literature (PubMed 96353982 ) for details.
 POLAcDNA polymerase A domain | |
|---|---|
| SMART ACC: | SM000482 |
| Description: | - |
| InterPro ACC: | IPR001098 |
| InterPro abstract: | |
| GO process: | DNA replication (GO:0006260) |
| GO function: | DNA binding (GO:0003677), DNA-directed DNA polymerase activity (GO:0003887) |
| Family alignment: | View the Family alignment or the Alignment consensus sequence |
| There are 28 198 POLAc domains in 28 190 proteins in SMART's NRDB database. | |
Taxonomic distribution of proteins containing POLAc domains
The tree below includes only several representative species and genera. The complete taxonomic breakdown of all proteins containing POLAc domains can be accessed here. Click the counts or percentage values to display the corresponding proteins.
Predicted cellular role
| Cellular role: | Replication |
|---|
Relevant references for this domain
Primary literature for the POLAc domain is listed below. Automatically-derived, secondary literature is also available.
KEGG pathways involving proteins which contain this domain
This information is based on the mapping of SMART genomic protein database to KEGG orthologous groups. Percentages are related to the number of proteins containing a POLAc domain which could be assigned to a KEGG orthologous group, and not all proteins containing POLAc domains. Please note that proteins can be included in multiple pathways, ie. the numbers below will not add to 100%.
KEGG pathways
KEGG orthologous groups
3D structures in PDB containing this domain
Links to other resources describing this domain
| InterPro | IPR001098 |
|---|---|
| PROSITE | DNA_POLYMERASE_A |
| Pfam | DNA_pol_A |