The Pfam:RhoGEF domain within your query sequence starts at position 49 and ends at position 110, and its E-value is 1.6e-9.

VLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDN
Pfam:RhoGEF

Pfam:RhoGEF
Pfam domain

Pfam ACC: