Consensus terms for the 14_3_3 domain 

NC31542_1        RDEYVYKAKLAEQAERYDEMAEAMKNLVENCLDEQQPKDELSVEERNLLSVAYKNAVGAR
CONSENSUS/80%    R-E.VYhAKLAEQAERYEEMVEFMEKVucss.......-ELTVEERNLLSVAYKNVIGAR
CONSENSUS/65%    REENVYMAKLAEQAERYEEMVEFMEKVAKss-.....sEELTVEERNLLSVAYKNVIGAR
CONSENSUS/50%    REENVYMAKLAEQAERYEEMVEFMEKVAKTsD.....oEELTVEERNLLSVAYKNVIGAR


NC31542_1        RASWRIISSVEQKELSKQ-HMQNKALAAEYRQKVEEELNKICHDILQLLTDKLIPKTS--
CONSENSUS/80%    RASWRIISSIEQKE-SRG NpspVu.I+-YRsKIEsELoKICDGILpLL-s+LlPuuo  
CONSENSUS/65%    RASWRIISSIEQKEESRG NED+VulIK-YRsKIEoELSKICDGILpLL-oHLlPSAS  
CONSENSUS/50%    RASWRIISSIEQKEESRG NEDHVAlIKDYRuKIETELSKICDGILKLLESHLIPSAS  


NC31542_1        DSESKVFYYKMKGDYYRYISEFSGEE-GKKQAADQAQESYQKATETAEGHSPATHPIRLG
CONSENSUS/80%    suESKVFYLKMKGDYaRYLAEFKsGA.ERK-AAEsThhuYKuAQDIA.A-LssTHPIRLG
CONSENSUS/65%    suESKVFYLKMKGDYHRYLAEFKTGA.ERKEAAEsTLlAYKSAQDIALA-LsPTHPIRLG
CONSENSUS/50%    uAESKVFYLKMKGDYHRYLAEFKTGA.ERKEAAENTLVAYKSAQDIALAELPPTHPIRLG


NC31542_1        LALNYS--VFFYEILNLPQQACEMAKRAFDDAITEFDNVSEDSYKDSTL-IMQLLRDNLT
CONSENSUS/80%    LALNaS  VFYYEILNSPDRACsLAKQAFD-AIuELDoLuEESYKDSTL IMQLLRDNLT
CONSENSUS/65%    LALNFS  VFYYEILNSPDRACsLAKQAFDEAIuELDTLGEESYKDSTL IMQLLRDNLT
CONSENSUS/50%    LALNFS  VFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTL IMQLLRDNLT


NC31542_1        LWTSDLQAD-QQQQEGG
CONSENSUS/80%    LWTSDhp-- st--I+E
CONSENSUS/65%    LWTSDhs-D uuDEI+E
CONSENSUS/50%    LWTSDlsDD uuDEIKE

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T