Consensus terms for the AP2 domain

O22259/1-64      LYRGIRQRPWG-KWAAEIRDPSK--------GVRVWLGTFKTADEAARAYDVAAIKIRG-
CONSENSUS/80%    .a+GVp.+.hG.+W.ucItcs..........ttclaLGoFsot-tAAhAYD.AAhhhhG.
CONSENSUS/65%    paRGVRpR.WG.KWsAEI+-stt........tpRlWLGTFsTsEcAApAYDtAAhthpG.
CONSENSUS/50%    +YRGVRpRpWG.KWsAEIR-Psp........+sRlWLGTF-TAE-AARAYDpAAhchRG.


O22259/1-64      -RKAKLNFPNTQVEE
CONSENSUS/80%    ..pAhhNFs....tt
CONSENSUS/65%    .ppAhhNFs.t..sp
CONSENSUS/50%    .scAclNFPssssss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T