Consensus terms for the APPLE domain

KAL_MO/21-104    CMTQL-YKNTFFRGGD---LAAIYTPDAQYCQKMCTFHPRCLLFSFLAVTPPKETNKRFG
CONSENSUS/80%    C......tshth.s.p...ht...s.sht.Cp.hCt.pstC.hFoa..tt..........
CONSENSUS/65%    Chpp...pslpapGss...lssshstssp.CpphCstpspCphFTasssp.........h
CONSENSUS/50%    Ctpph.hcslcapGs-...lssltsssAptCpctCopcspCphFTFssssh.p..p.t.s


KAL_MO/21-104    CFMKESITGTLP-RIHR-TGAISGHSLKQC
CONSENSUS/80%    ChL+...sss....h....shhSG...htC
CONSENSUS/65%    ChLK...susss.thsp.psslSG..hppC
CONSENSUS/50%    ChLKps.oGoss.plsp.psulSG.oh+sC

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T