Consensus terms for the ARF domain 

arf6_chick       ----MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN
CONSENSUS/80%    ....huplhptlFGpKEMRILMlGLDuAGKTTlLYKLKLGp.lTTIPTlGFNVETVpYKN
CONSENSUS/65%    MG.hhuKLFSsLFGNKEMRILMVGLDAAGKTTILYKLKLGElVTTIPTIGFNVETVpYKN
CONSENSUS/50%    MG.hhuKLFSsLFGNKEMRILMVGLDAAGKTTILYKLKLGElVTTIPTIGFNVETVpYKN


arf6_chick       VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRD--RIDEARQELHRIINDREMRD
CONSENSUS/80%    lpFsVWDVGGQD+IRsLWRHYapsTpGlIFVlDssDRp  RlsEARp.h.Rhls-cEhRs
CONSENSUS/65%    ISFTVWDVGGQDKIRPLWRHYYpNTQGLIFVVDSNDR-  RIsEAREELpRMLNEDELRD
CONSENSUS/50%    ISFTVWDVGGQDKIRPLWRHYYpNTQGLIFVVDSNDR-  RIsEAREELpRMLNEDELRD


arf6_chick       AIILIFANKQDLPDAMKPHEIQEKLGLTRIR------------DRNW----------YVQ
CONSENSUS/80%    AlhLlFANKQDLPpAMpstEIp-KLGLpplR            pRsW          alQ
CONSENSUS/65%    AVlLVFANKQDLP-AMsAAEITEKLGLHSIR            cRNW          YIQ
CONSENSUS/50%    AVlLVFANKQDLP-AMsAAEITEKLGLHSIR            cRNW          YIQ


arf6_chick       PSCATTGDGLYEGLTWLTSNYKS--
CONSENSUS/80%    soCAToG-GLYEGLpWLosph+s..
CONSENSUS/65%    uTCATSGDGLYEGL-WLSNNLKNQp
CONSENSUS/50%    uTCATSGDGLYEGL-WLSNNLKNQp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T