Consensus terms for the Amelin domain 

Q6Y4V4_XENLA/1-0 ----------MELLALVFCLISTAIAYPMHQHTPGT-----QGLASISLETMR-QQAADT
CONSENSUS/80%    ..........Mp.hhLhhsLlthu.AhPha.ppsGh......GhsShSLE.hR.Q.ut.p
CONSENSUS/65%    ..........Mc.hhLhhCLlphuhAhPhaPQpsGs......GhASlSLETMR.Q.uu.p
CONSENSUS/50%    ..........McshhLlLCLLphuhAlPhaPQpPGT......GMASlSLETMR.QhGu.Q


Q6Y4V4_XENLA/1-0 LTAPLSQISRFGYNDPYSVLWLHGLLPPHSSYPWLHQRPQLSDNQQFEYALPIHPPPLPG
CONSENSUS/80%    .hs.LsQhuRasascshsslWhpGLLPP.S.hPW...RPp..-sQ...............
CONSENSUS/65%    ths.LSQhSRaGascsassLWhpGLLPPHSSaPWh..RPpppEsQ.....hPlHPPPLPu
CONSENSUS/50%    thNsLSQYSRFGaGcsaNSLWLHGLLPPHSSaPWh..RPpEHETQQaEYulPVHPPPLPS


Q6Y4V4_XENLA/1-0 AQSPAQTEKAGQ----HTQNIPQQPQAAASTDQLSHQPSLPLGFPILQQADP-AITPPKG
CONSENSUS/80%    .Qss.ps.pst........p.s..st.tst........sh..t...LQpu-..s.h..ps
CONSENSUS/65%    .QsshQPpQPG.p....h.pss.hsshQssspp.s.pPPh..Gp.PLQpuEh.shsp.Ql
CONSENSUS/50%    .QPSLQPpQPGhK...PFLQsTsssshQsosQKsusQPPla.Gp.PLQQAEL.PhlppQV


Q6Y4V4_XENLA/1-0 GPVDGQIQT-VALYMYQTIMNKLLQ-------------------------QGAGEMMPDP
CONSENSUS/80%    uPs-t..ps.lshh.ats.....h............................luc.hsc.
CONSENSUS/65%    uPu-t..ps.lPhh-aus..s.sl..........................atIu+hls+.
CONSENSUS/50%    APoDpPlpsELPlhDFADhQsPsl..........................FsIA+hlS+.


Q6Y4V4_XENLA/1-0 ASTPPVHQQHPYPGLFFMQYGGGPGGPP-ARLGAMSSEEITGGRAGAAHAFSSLYPGLLG
CONSENSUS/80%    ushs.s+....YPGhhahpYGus.hssP.ARlGhhSSEEh.GuR.ssshsauuhhPGhhG
CONSENSUS/65%    uPhP.s+.sthYPGhFYMsYGuNQhssP.ARLGhMSSEEhsGGR.GushAYGulaPGhhG
CONSENSUS/50%    GPMPpNKQspLYPGlFYMoYGANQLuAP.ARLGhMSSEEhsGGR.GuPhAYGuLaPGasG


Q6Y4V4_XENLA/1-0 MGPGPGSQPQNPALQGDFTIEDDSPIAGGKPT---------VFKGPIETPQAVGPSLIIP
CONSENSUS/80%    ht.t.tt.PpsPshtGDFTlE.DoPhuusKss.pt......sptuPh.psp.ss.pp.h.
CONSENSUS/65%    ht.shtuhPQNPshtGDFTlE.DSPlAusKustpt...p.hspsSPl.pspsss.psshh
CONSENSUS/50%    MRPshcGhPQNPAhuGDFTlEsDSPVAATKGPEpG...EGGupGSPlpEspsscsEssAL


Q6Y4V4_XENLA/1-0 GSEGNPNGQGETVAFPNINLPNFAFNPQSQSKLPP-GVTPANA-PRLTYDTGAGFVPFAL
CONSENSUS/80%    hsphsPsuptthlu.Pp.plPshuhsPtup.ph...tVTPssA.PhhT.thutsa.sauh
CONSENSUS/65%    Lo-hsPuupsGhlAhPNsslPshAhsPsGp.+t...sVTPssAsPhlT.-lu-sa.Tauu
CONSENSUS/50%    LSElsPuuHuGLLAFPNDNlPNhARuPuGQp+tsP.uVTPAAADPLlTP-LA-lYcTYGA


Q6Y4V4_XENLA/1-0 DDTIPFSVQRENVITGEMTQANNAKTIDSPIMREVHLQNHNNYFQEP
CONSENSUS/80%    D.Thshu.ptEsshs.pMs.ss.ts.hsushhppsph.pcs.aFQEP
CONSENSUS/65%    DsTsPluhQcEsTh-sTMoPssppssMsuNtspQPph.pcsW+FQEP
CONSENSUS/50%    DsTTPLGlQcEsTMDsTMTP-oppTsMPGNKscQPQlhH-sWHFQEP

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T