Consensus terms for the B12-binding_2 domain

234267.Acid_6968_from_1_to_84MPDLEKLHEAVIEGDWKGAAAMTRAAIADG------------------------------
CONSENSUS/80%    ..h.ppltptlhps.tp.h.t.hpphhtt...............................
CONSENSUS/65%    hsl.ccLtpsllcGppptl.p.sccuhpph..............................
CONSENSUS/50%    tslp-+LpcAllcG-c-tlpcslc-ALsps..............................


234267.Acid_6968_from_1_to_84--VAPLTIVTGCLVPAMDEVGRRFEREEYFVPEMLISARAMKAAM-EIVR-PLLAAIG
CONSENSUS/80%    ...tshpllpt.Lh.uMp.VGchattsphhlPpll.uucsMptuh.thLp.shhtttt
CONSENSUS/65%    ..hpPlclIppsLhsGMphVGcLFtpGchaLPpllhSAcsM+tul.shLp.Phhpppp
CONSENSUS/50%    ..tcPl-IIsssLhsGMclVG-LFssGchFLPpVlpSA-sMKsAV.uhLc.Palccpc

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T