Consensus terms for the C2 domain

JC5772/1-104     VTQVHVLGAAGLKDSPT-------------------------------------------
CONSENSUS/80%    .h.l.lhpsptl................................................
CONSENSUS/65%    hlplplhpupsL.ths............................................
CONSENSUS/50%    pLplpllpAcsLsspch...........................................


JC5772/1-104     -GANSYVIIKCEGD----------------------------------------------
CONSENSUS/80%    ...ssas.h.h.................................................
CONSENSUS/65%    .hs-sYlplplhs...............................................
CONSENSUS/50%    tpsDPYVclplssttt............................................


JC5772/1-104     ----------------------------------------------------KVRSAVQK
CONSENSUS/80%    .......................................................pTphh
CONSENSUS/65%    .....................................................hh+Tpsh
CONSENSUS/50%    .....................................................pt+Tclh


JC5772/1-104     GTS----------TPEYNV---KGIFYRKKL----------------------SQPITVQ
CONSENSUS/80%    tps..........sP.app...th.h.h..........................t.l.ht
CONSENSUS/65%    pps..........sPhWs-...ph.hph.........................tphlplp
CONSENSUS/50%    cssh.........NPpWsE...sFpFslssst.....................sspLplp


JC5772/1-104     VWNHRVL----------------KDEFLGQVHLKADP---------------------DN
CONSENSUS/80%    lhs.p......................pp.lGth.h......................ht
CONSENSUS/65%    Vh-psth...................tsphlGpstls.....................lp
CONSENSUS/50%    VaDc-pht..................pcchlGpspls.....................ls


JC5772/1-104     LQALHTLHLRD
CONSENSUS/80%    ph..t......
CONSENSUS/65%    plhttttt.hh
CONSENSUS/50%    cltsssppsth

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T