Consensus terms for the CBS domain

IMP1_HUMAN-1     DPVVLSPSHTVGDVLEAKMRH---GFSGIPITETGT--MGSKLVGIVTSRDIDFLAE
CONSENSUS/80%    thhsl..p.tl.pshphhhpt...thtth.llpt......tplhGhlshtclh.hh.
CONSENSUS/65%    sshslpsspsltcshphhhpp...tlpplsVVcp......scllGllotpDllphhh
CONSENSUS/50%    clloVssssslp-slplhpcp...slppLPVVDst.....s+LlGIlTppDllpslt

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T