Consensus terms for the CH domain

cef26f4_1        RRNVLLMWVQEKLELY----------------------SDQLTVSNFSSDWTDCRAFCAL
CONSENSUS/80%    .tpthhtWhpthht.............................htph.pshpsGhhhhtL
CONSENSUS/65%    tcpthhpWhppthtt.........................t.thpshtpshpDGhhLspL
CONSENSUS/50%    pccsllcWlppplspt........................psslssFssslpDGlsLspL


cef26f4_1        LYDLFP---DTMPDVTVS--------PIVGDCISRCRRTFQLLEIPFDERALGISSPTAD
CONSENSUS/80%    hp.h.s...t.h................................hpphp.hhp.hpt...
CONSENSUS/65%    lptltP...pthsttp.......................tphpthpNlphhlphscph..
CONSENSUS/50%    lcslpP...cslsppsht....................hsphpphcNlspsLssscch..


cef26f4_1        S---GADEDSSSACSVITG-------LTDWRYIMNTVFML-
CONSENSUS/80%    . ........htstclht...   .....hthhh.l..h..
CONSENSUS/65%    . ..hsph.hhpspDlhp...   .tp..hsllhslhth..
CONSENSUS/50%    . ..hspsshlsscDls-s..   .p+shhullhsLhph..

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T