Consensus terms for the CRA domain

CAAC010/1-97     EQTEEPVLYFREQLM---KHGKRPDDE-------KMDI--IEKIFTLMVYGSE-------
CONSENSUS/80%    t.h.psltaupp.ht....h.tt.............tp..lpphhshlha..........
CONSENSUS/65%    tthpcAlpaupphhs...phsppp...........hpp..lpchhuLLsatp........
CONSENSUS/50%    sslc-AlpYu+cplu...passcstt.........hc-..LccshuLLAasss.......


CAAC010/1-97     -----ENVNRIYFEQS-------EREKTAKIVNSAMLGV-AGKSR--------QSHIDFL
CONSENSUS/80%    ......p.ht.hhp........ .h..hhp.hptthht...t............s.lt.h
CONSENSUS/65%    ....ptsshtthlp.p...... .ppplsptlspslLph..stp..........s.Lphh
CONSENSUS/50%    ....psushsplLsss...... pRpplucplNpslLpth.spsp........posLcpl


CAAC010/1-97     AKSIIWGKNDIVSRQTP
CONSENSUS/80%    ht.hh.h...h.p....
CONSENSUS/65%    lptthhshtphtp.t..
CONSENSUS/50%    lstspsshssLpppsst

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T