Consensus terms for the CTLH domain

O22730/78-135    TITDRMAV-KKAVQNGNVEDAIEKVNDLNPEILDTNP-----------------------
CONSENSUS/80%    .h.ph..h..p.l.ttphtts.phhtt.................................
CONSENSUS/65%    .h.phptl.pchlhpGphspslphhpphp..h.pptt.......................
CONSENSUS/50%    phpstppl.cctlpsGch-sAlchlsshpsplhppps.......................


O22730/78-135    ---ELFFHLQQQRLIELIRQGKTEE
CONSENSUS/80%    ...th.h.lh..phlchlp.tp..t
CONSENSUS/65%    ...pl.FpLpptchlEhlcttphtp
CONSENSUS/50%    ...clpFcL+pQ+alELl+pscspc

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T