Consensus terms for the CYCLIN domain

O77212/1-85      DWLVEVAEEYKL--------------HRETLFLAVNYIDRFLS--KISVLR--GKLQLVG
CONSENSUS/80%    .hl.ph.tthth.........  .....ph..hsh.hhchhh....thh....h..phlu
CONSENSUS/65%    palhchtpthph.........  ...s.pshhhuh.lh-hhl...hphhp...hp.phlu
CONSENSUS/50%    saLtclscphsl.........  ...spcstpLAhplh-+sLs.tpshlp...tpsphlA


O77212/1-85      AASMFLAAKYEEIY----------PPDVTEFAYITDD-----------------------
CONSENSUS/80%    ssshhlAtph.p................p...h.t.........................
CONSENSUS/65%    suslalAs+h.pht...........ht.phhthssh........................
CONSENSUS/50%    AuulalAsKhpcts..........shspslhphsss........................


O77212/1-85      -------TYDKKQILRMEHLILK
CONSENSUS/80%    .........p.tplhth.h.hhp
CONSENSUS/65%    .........stpplhph.phlhp
CONSENSUS/50%    .........spscltptpctllc

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T