Consensus terms for the DDE_2 domain 

TRA_HAEIN/267-485VAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTWLWQDVRTRKVLAARTDKSENTDTIRL
CONSENSUS/80%    VthLpAMpWINGDGY.HNVaVRa.sG-lhRPKTWhWQDV+TRKlLuhRsDhSENhDoIRL
CONSENSUS/65%    VthLpAMpWINGDGY.HNVaVRa.sG-lhRPKTWhWQDV+TRKlLuhRsDhSENhDoIRL
CONSENSUS/50%    VAMLDAMQWINGDGYLHNVWVRWPDGDVKRPKTWLWQDVKTRKVLGARTDKSENTDSIRL


TRA_HAEIN/267-485SLLDVISRYGLPK..HLTIDNTRAAANKKMTGGVKNRYRYQVNENEVQGIIPALGIELHW
CONSENSUS/80%    ShhDVloRYGlPc..HlTIDNTRuAANKhhTGGs.NRYRapVpEs-spGlh.hhGhchHW
CONSENSUS/65%    ShhDVloRYGlPc..HlTIDNTRuAANKhhTGGs.NRYRapVpEs-spGlh.hhGhchHW
CONSENSUS/50%    SLLDVVSRYGLPKDFHLTIDNTRGAANKKLTGGAKNRYRYKVKEDDPKGLFLALGAKLHW


TRA_HAEIN/267-485TSIQFGKGRGQAKPIERAFSHGGLGDYVDKHLLLRGAYAGANAYEKPDYDGKNGAEQPVD
CONSENSUS/80%    TSl.hGKGhGQAKPlERAFuhGGLt-YVDKH.hLtGAYsGsNs.tKPD....Nhu-psVD
CONSENSUS/65%    TSl.hGKGhGQAKPlERAFuhGGLt-YVDKH.hLtGAYsGsNs.tKPD....Nhu-psVD
CONSENSUS/50%    TSVQAGKGRGQAKPVERAFSVGGLGDYVDKHLALAGAYAGANAQAKPDYDGKNGGDQAVD


TRA_HAEIN/267-485YATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAFERDWA
CONSENSUS/80%    hthFLhsLtpGlt.aNshssR.TEhCuGK.Sas-sFER-aA
CONSENSUS/65%    hthFLhsLtpGlt.aNshssR.TEhCuGK.Sas-sFER-aA
CONSENSUS/50%    AALFLKALAQGVAMWNARGGRLTEMCGGKSSYDDAFERDYA

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T