Consensus terms for the DEATH domain

710552/1-95      SMSPQSPCERTDIRMAIVADH---LGLSWTELARELNF-----SVDEINQIRVENPN---
CONSENSUS/80%    .....t........h..hhp.....htpWt.hsptlth.......t.hp.ht.p......
CONSENSUS/65%    .stshphpp.sptphtthhsh...hspsWppLAppLsh.....pppplpthpppss....
CONSENSUS/50%    sssstslsssscpclspltct...suscW+cLA+cLsl.....s-scIcplcscsst...


710552/1-95      -------------------------SLISQSFMLLKKWVTRDGKN------ATTDALTSV
CONSENSUS/80%    ...............................h.hLp.W..ttt........tshttLhts
CONSENSUS/65%    ............................p.shtlLptWhtpps........sslssLhps
CONSENSUS/50%    ..........................htppstpLLcpWpppcGpp......uolssLlpA


710552/1-95      LTKINRIDIVTLLEGPI
CONSENSUS/80%    Lpphth.thhp.h.t..
CONSENSUS/65%    Lpphshpchschltpth
CONSENSUS/50%    Lcchups-sl-tlpssh

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T