Consensus terms for the DEFSN domain

DEF1_CAVPO/1-2   CI-----CTTRTCRFP-YRRLGTCIFQNRVYTFCC
CONSENSUS/80%    Ch.....Cp..hC..t..p..GsC...hh.hhhCC
CONSENSUS/65%    Ch.....CRhhtChtt.E+hhGsC...shhashCC
CONSENSUS/50%    Ch.....CRptpCssp.ERphGTCthtGthashCC

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T