Consensus terms for the DEP domain

DVL2_HUMAN/433-  PESGLEVR-DRMWLKITIPNAFLGSDVVDWLYHHVEG-----------------------
CONSENSUS/80%    ..tsh.ht...h..hhhh.psh.Gtphlphlhp.h.........................
CONSENSUS/65%    .psslthp..pphhhphh.pshsGp-hVsWLhppht........................
CONSENSUS/50%    hpsulplc.p++hphpphsssFsGs-lVcWLhsphp........................


DVL2_HUMAN/433-  FPERREARKYASGLLKAGLIRHTV------------NKITFSE---QCYYVFGD
CONSENSUS/80%    ..p.ttuhthsp.hhttthh..h.............tp..h.....t.hY.h.t
CONSENSUS/65%    h.scppAhpluptllppshlp.ls............pptpFpcp..pthYpass
CONSENSUS/50%    lpsRscAlplupsLlcpGalccls............scpsFp-p..pshYpFss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T