Consensus terms for the DoH domain

Q9VH23/292-454   HKDMQVSWEVFG--PQITFQLSGQVGG----NDYMSFGISGSD-VS-SQMIGSDVVVAYI
CONSENSUS/80%    t.th.htaph.t..t.lthth.st.......stahuhGhs.p.....t.M.ssphhhhh.
CONSENSUS/65%    stphhlpaphts..splthplpsss......ssasuhGhuss.....ttMsssssllshh
CONSENSUS/50%    ssshtlpWshssp.sslphplpussst....ssWlAlGFSsc.....spMssuDlllshs


Q9VH23/292-454   DD---------------------------IRGYTVDYN--ITSLAPCVQVLGQNKGVCRD
CONSENSUS/80%    .s...........................sts.h.s....h.s.t..............t
CONSENSUS/65%    ps...........................spshhpshh..hsshs..............c
CONSENSUS/50%    sss..........................Gpsplpsta..ssupussh..........t-


Q9VH23/292-454   DVVGGLDSFQLN-------TYSRKDGINT-ISFRRTLKSSDD------GDKEIFLDRSNY
CONSENSUS/80%    .t.sh...............ht..sshhh.h.hph.hts................ttth.
CONSENSUS/65%    hp.shps............psphpsshhh.hthp+plssst..............ssshp
CONSENSUS/50%    sppsspss...........sushssGslh.lpFpRclssscs.........hhhsssshp


Q9VH23/292-454   VIWAFGP-----------LDSNNEPAFHTY--------YPKSDIVIDFNTTEP
CONSENSUS/80%    hhhs.G................t..thHt............t.t.hph.p...
CONSENSUS/65%    hlashG.............sttsthshHs...........tshphlplhpspt
CONSENSUS/50%    llaAtGs............ssssplshHsps.........sospplslsssss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T