Consensus terms for the EPEND domain 

EPD1_CARAU       QPCHAPPLTSGTMKVVSTGGHDLESGEFSYDSKANKFRFVEDTAHANKTSHMD-VLIHFE
CONSENSUS/80%    Q.CpSPshTushhhhs.TGGc.hAoGcasYDSpspKhRFsEsphHhNKTpHh-.hLhhFE
CONSENSUS/65%    Q.CpSPshTushhhls.TGGc.hAoGcaSYDSpspKhRFsEsshHhNKTpHh-.hLhhFE
CONSENSUS/50%    QPCHSPsLTSGTMKVlSTGGHDLASGEFSYDSKAsKFRFVEDshHANKTSHlD.VLlHFE


EPD1_CARAU       EGVLYEIDSKNESCKKETLQFRKHLMEIPPDATHESEIYMGSPSITEQGLRVRVWNGKFP
CONSENSUS/80%    EGlhY-ID.KNpSCKK.oLp.+tHhhElPssAsHpsElahGSsolpEpsl+VplW.GplP
CONSENSUS/65%    EGVhY-ID.KNpSCKK.oLQ.+tHhhElPssAsHpsElahGSsolpEpsl+VplWpGplP
CONSENSUS/50%    EGVLYEIDSKNESCKKETLQFRKHLMEIPPDATHESElYMGSPolsEQGLRVRVWsGKlP


EPD1_CARAU       ELHAHYSMSTTSCGCLPVSGSYHGE-KKDLHFSFFGVETEVDD-LQVFVPPAYCEGVAFE
CONSENSUS/80%    Eh+upYSluTTsstCLPlSs.Y.s-.phsLhFS..tV.TEVcs..psFs.PuaCEuVthE
CONSENSUS/65%    Eh+upYSlSTTsssCLPlSs.Y.s-.phsLlFS..tV.TEVcs..pVFs.PuaCEGVthE
CONSENSUS/50%    ELHAHYSLSTTSCGCLPVSGSYaGD.KKDLLFSFFGVETEVDD.PQVFVPPAYCEGVuFE


EPD1_CARAU       EAPDD--HSFFDLFHD-
CONSENSUS/80%    EsPcs..psFFslFps.
CONSENSUS/65%    EsP-s..psFFsLFps.
CONSENSUS/50%    EAPDD..HSFFDLFHD.

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T