Consensus terms for the FAS1 domain

Q9NH96/210-307   TVFAPTNEAFAKIPAEKL---------------KEILKNI--------PLLTKILKYHVV
CONSENSUS/80%    TlhsPpspAhtt......................th................thl.hHhl
CONSENSUS/65%    TlFsPsspAFpph....................pplhtp............tpllphHll
CONSENSUS/50%    TlFAPo-cAFsclssthh...............sslpsst..........hpplLpaHll


Q9NH96/210-307   S---GTFCSAGLTN----------GATVPTLE---------GSDVTVHISG---------
CONSENSUS/80%    ....thh..tth.t.............h.oht.........s..l.ht..t.........
CONSENSUS/65%    s...thhh.pslhs..........ttthpoht.........stplplptps.........
CONSENSUS/50%    s...splssssLps..........ssslsTls.........Gsclplssss.........


Q9NH96/210-307   --GSVTVNNA---------------VVVFV--DIPVTN-------GVVHVIDTVL-IPK
CONSENSUS/80%    ....hhhs..................lht...sh..ts.......hhlahlspll.hs.
CONSENSUS/65%    ..tthhlss................tlhps..sh.sss.......uslahlDplL.hP.
CONSENSUS/50%    ..sslplNss...............pllps..DlsssN.......GllHsIDcVL.lPh

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T