Consensus terms for the FH domain

O60129/1-98      NKKPPYS-YSVMIAQAILSSSECMMTLSNIYSWISTHYPYYRTTKS-----GWQ------
CONSENSUS/80%    ..+PshS.Y.tLIthAl.pusppplsLstIYpal.ppasaappt.t.....tWp......
CONSENSUS/65%    .tKPPaS.YhsLIshAIppSPp+plTLstIYpaIhppFPaa+pstp.....uWp......
CONSENSUS/50%    tpKPPYS.YsuLIuMAIpsSP-K+LTLupIYcaIpcpFPYYRcsss.....GWQ......


O60129/1-98      ----------NSIRHNLSLNKAFRKVPR-----------KSGEQGK---GMKWSIVPEFR
CONSENSUS/80%    ..........NSlRHNLShpcpFh+l.p.............tt.st...GpaWhlps.t.
CONSENSUS/65%    ..........NSIRHNLSLNcCFhKl.+...........p.spsuK...GsaWslcPtst
CONSENSUS/50%    ..........NSIRHNLSLN-CFlKVsR...........cssssGK...GsaWslcPssp


O60129/1-98      EE-FIAKT
CONSENSUS/80%    ...h.ttt
CONSENSUS/65%    .phhppsp
CONSENSUS/50%    .phF-sGs

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T