Consensus terms for the FN3 domain

APU_THEET/2-0    P-TALG---LQQPGIESS------RVTLNWS--LSTDNVA--------------------
CONSENSUS/80%    ...s.t...hth...ttt......th.lpWp...s..................    ...
CONSENSUS/65%    .ssPts...lphpthsps......slplpWp...stts...............    ...
CONSENSUS/50%    sssPss...lplssssss......olslsWs..sPsss...............    ...


APU_THEET/2-0    ------IYGYEIYKSLSETGPF----------------------------------VKIA
CONSENSUS/80%    ......hhth.................................................h
CONSENSUS/65%    ..htthhhtahhphtt........................................htph
CONSENSUS/50%    ..hsshllpYplptpstt.....................................thppl


APU_THEET/2-0    TVADTV--------------------------YNYVDTD--VVNG----KVYYYKVVAVD
CONSENSUS/80%    .................................th.htt..L..t....t.Y.hplhsh.
CONSENSUS/65%    ttt.............................pphtlps..Lpss....spYphpltAhs
CONSENSUS/50%    ssss............................sshslss..LpPs....spYplcVpAhs


APU_THEET/2-0    T--SFNR
CONSENSUS/80%    ....s.s
CONSENSUS/65%    ...tG.u
CONSENSUS/50%    t..sGpu

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T