Consensus terms for the GDNF domain

10116.ENSRNOP00000043286_from_24_to_102/1-79CAYFM-RQCLTDTD-GCK-----------------------------QSWRSME------
CONSENSUS/80%    Chphh.p.Ct.s....Ct.............................phh.th.......
CONSENSUS/65%    Clpsh.ptCpts.h..Cp.............................pthtpah......
CONSENSUS/50%    CLcut.csCpsDsp..Cc.............................sphssah......


10116.ENSRNOP00000043286_from_24_to_102/1-79----------DACLVSGN------------------------------PGDSCKINNPLP
CONSENSUS/80%    ..........ttC..............................................t
CONSENSUS/65%    ..........ppCts.....................................t...t.tt
CONSENSUS/50%    ..........ssCsst.t...............................ts.p...stss


10116.ENSRNOP00000043286_from_24_to_102/1-79CNLSIQ-SL------VEKHFQFKG-----------------------CLCT------DDL
CONSENSUS/80%    C..tht ........th..p..h........................C.Ct.......p.
CONSENSUS/65%    Chpshp ........ttthpsha........................CsCp.....tpcp
CONSENSUS/50%    Ctpuhs ........spshsshas.....stt...h..h........CsCp..pt.ppcp


10116.ENSRNOP00000043286_from_24_to_102/1-79HCT-VNK--IFGKKC
CONSENSUS/80%    .C.thhh..hh...s
CONSENSUS/65%    tCtphht..hhts.C
CONSENSUS/50%    pCtphpc.phpsssC

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T