Consensus terms for the GIYc domain

1174920/1-82     EPGVYRMYD----------------DKDQVIYVG----KAKDLKKRLSSYFRKNL-----
CONSENSUS/80%    .shhhhhht..................s..hYlG.......phtpRhtpah.........
CONSENSUS/65%    psslYhhhp.................tsthhYlG....pstslppRlppaht.t......
CONSENSUS/50%    psGlYhhts................pssstlYlG....pussLcpRlppHhpts......


1174920/1-82     ------SSKKTEALVASI-----HHIDTTLTSSET-------------EALLLEHNFIKL
CONSENSUS/80%    .........h..hhht.........hth.hh.....................hEt.hhp.
CONSENSUS/65%    ......tphhhphlhphs.....tphphhhht................thh.hEpthlpp
CONSENSUS/50%    ......ssthpptlhcpu.....pshchplhpp.p.............pthhhEsplIcp


1174920/1-82     YQP---------------RYNVLLRD
CONSENSUS/80%    h..................hNhhh.t
CONSENSUS/65%    hts...............taNlhhts
CONSENSUS/50%    aps...............paNlhhps

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T