Consensus terms for the HDc domain

5834361/1-386    HFRVRLTHSLEVAQIGRTIARVLR------------------------------------
CONSENSUS/80%    ....hhtHshtsh.hh..hh........................................
CONSENSUS/65%    tstshhpHshpVsthsttlspth.....................................
CONSENSUS/50%    pspsshpHolpVuplupplucphs....................................


5834361/1-386    ---------------LNEDLTEALCLAHDLGHPPFGHIGENILKQALK------------
CONSENSUS/80%    ...................hhhhsuhhHDlsc............................
CONSENSUS/65%    ................p.thhhhuulhHDlu+shh.t.......................
CONSENSUS/50%    ...............hcsptlhhAALLHDlG+shhsphh.....................


5834361/1-386    -------DAGGFDHNAHSLRILTH----------------------LESPYPRWSG----
CONSENSUS/80%    .............p..ht..hh......................................
CONSENSUS/65%    ............p+thhstthhh...........................htphhhth..
CONSENSUS/50%    ..........htsHsthusphlp..........................thsphstphh.


5834361/1-386    -------------------------------------NKIDPNLIGALIDENQNIQ----
CONSENSUS/80%    ...........................................h..c.............
CONSENSUS/65%    ...........................................htt+p.h..........
CONSENSUS/50%    ..........................................slppHptt..........


5834361/1-386    ------------------LSAVDDAFPLELTSWPSLEAQVAALSDDIAYDNHDLDDGLR
CONSENSUS/80%    .......................................hh..sD.ht.hh........
CONSENSUS/65%    ..................................s..shhlphADthsshht.tthtth
CONSENSUS/50%    ..............................tpthshpspllpsADplcstpsstphppt

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T