Consensus terms for the HLH domain

26|O77026/1-80   NARER---NRVKQVNN-GFSQLRQHIPAAVIADLSN------------------------
CONSENSUS/80%    s.hE+...pRhpphst.th.tLpphls.................................
CONSENSUS/65%    shtER...pRppplNp.thppL+phlP.................................
CONSENSUS/50%    stpER...+RRcclNc.sappL+cllPphs..............................


26|O77026/1-80   ---GRRGIGPGANKKLSKVSTLKMAVEYI--RRLQKVLHE
CONSENSUS/80%    ............tp+hsKhthLp.shpal..t.lpt..t.
CONSENSUS/65%    ............sp+hsKhplLchAhpYl..ppLppthpp
CONSENSUS/50%    ...........sspKlsKssILcpAlcYI..cpLppplpp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T