Consensus terms for the HNHc domain

Q38028/1-51      YSRTEIMRRWG---YRCA----YCDAKAT---------------HLDHVHPLSKGG----
CONSENSUS/80%    ..tt.hh.p.......s.....hpt..................hphcHl...t.......
CONSENSUS/65%    phpthhhpp......hCt....hCst..t..............hplcHlhshpts.....
CONSENSUS/50%    ph+phlhp+t....hsCs....hCspshs..............hclcHIpPpspuu....


Q38028/1-51      ----------ADAAHNMLPAC-AKCNL
CONSENSUS/80%    ............t.pNh..hs..tpp.
CONSENSUS/65%    ..........ssshsNlhhhs.tppph
CONSENSUS/50%    ..........ssshcNLtslC.spCHp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T