Consensus terms for the HisKA domain

O31138/1-76      IKSEFLANMSHEIRTPLNGILGFTNLLQK----------------------------SEL
CONSENSUS/80%    .htphhs.hsH-l+sPlssl.h.hphh.t.........  ....................
CONSENSUS/65%    tppphhusluHElRsPLsslhshhphltp.........  ..................th
CONSENSUS/50%    pcscalAsloHELRTPLsuIpuhsclLpc.........  .................ssh


O31138/1-76      SPRQ------------------QDYLTTIQKSAES-LLGIINEILDFSKIEAG
CONSENSUS/80%    .......................t.hp.h.pp.pp.h.tllpphh.hsp.pt.
CONSENSUS/65%    sttp..................pphlptltppspp.htpllpslLphu+hptt
CONSENSUS/50%    sscp..................pchlcslpcssc+.lppLls-lLclu+h-ss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T