Consensus terms for the IG_like domain

HV07_MOUSE/1-11  PGAELVKP--GASVKLSCKASGYT-------------FTSYWMHWVKQ----RPGRGLEW
CONSENSUS/80%    .....h....Gpph.l.C.h.t....................h.ahh.............
CONSENSUS/65%    stshhst...GpslplpCpsps................ststhpWhpp..........p.
CONSENSUS/50%    ssshslpt..GpslsLsCpssu...............ssssplpWh+p........tsph


HV07_MOUSE/1-11  IGRIDPNSGGTKYN---------EKFKSKATLTVDKPS----------------STAYMQ
CONSENSUS/80%    ..............................thth........................l.
CONSENSUS/65%    l...........................ttphphpt...................thtLp
CONSENSUS/50%    lh..........................ss+hslsppt................tsssLp


HV07_MOUSE/1-11  LSSLTSEDS-----AVYYCARY------------DYYGSSYFDYWG--QGTTLTVS
CONSENSUS/80%    l.thp.tct.....u.YhC.h........................t....h.l.l.
CONSENSUS/65%    lpslp.pDs.....GhYhCtsp................st.tthts...ssplpV.
CONSENSUS/50%    IsslptsDs.....GsYpCpss................sstsstpu...sspLpVp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T