Consensus terms for the IL2 domain 

IL2_FELCA        MYKIQLLSCIALTLILVTNSAPASSS--------------TKETQQQLEQLLLDLRLLLN
CONSENSUS/80%    ....................APsSSS...............tpp.pplc.LLhDLp.LLp
CONSENSUS/65%    MYph.LhSClsLTLhLlssSAPTSSS..............sppTQpcLEpLLhDLQhLLp
CONSENSUS/50%    MYKhQLLSClALTLlLLTNSAPTSSS..............TKQTQQ+LEQLLLDLQLLLE


IL2_FELCA        GVNNPENPKLSRMLTFKFYVPKK-ATELTHLQCLVEELKPLEEVLYLAQSKNFHLNHIKE
CONSENSUS/80%    thps..N.+Ls+MhphphY.PK..soELpcLpCL.-ELt.lcpVL.Ls.pKsh.h.chcp
CONSENSUS/65%    tVpN.cN.KLsRMLTFKFYhPKh.ATELpHLQCL.EEL+sLEcVLsLApSKNFpLpchK-
CONSENSUS/50%    GVcNPENLKLPRMLTFKFYlPKp.ATELKHLQCLEEELKPLEEVLDLAQSKNFsLcHIKD


IL2_FELCA        LMSNINVTVLKLKGSETRFTCNYDDETATIVEFLNKWITFCQSIFSTLT-
CONSENSUS/80%    .hsNIphhVlpLpGS-stF.Cph-DtosphV-FLp+WhsFCQpIhSp.s.
CONSENSUS/65%    hhSNIpVTVLcLKGSETpFsCpaDDEosslVEFLp+WIsFCQSIhSThT.
CONSENSUS/50%    FISNINVTVLKLKGSETRFTC-YDDESATIVEFLNKWIAFCQSIaSTLT.

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T