Consensus terms for the IRF domain

IRF7_MOUSE/1-1   RGVQRVLFGDWLLGEVSSGQYEG-LQWLNEARTVFRVPWKHFGRRDLD-EEDAQIFKAWA
CONSENSUS/80%    hs.tt.tht.Wlltphpss.a.G.l.W.scp+phhplPWp+.tttshp.pt-t.ha.sas
CONSENSUS/65%    hsspphpl+sWLltplsSupaPG.LhWhsc-+ohFRlPWpHsscpshs.ppDstlFcsas
CONSENSUS/50%    tusp+s+LRsWLlspl-SGpYPG.LpWlDEEKTlFRIPW+Hsu+pchs.-cDuslF+AWA


IRF7_MOUSE/1-1   VARGRWPPSGVNL-PPPEAEAAERRERRGWKTNFRCALHSTGRFILRQDNSG-DPVDPHK
CONSENSUS/80%    ..pGhh..u.pp...............tthhtphhpthpp.t.h....chst...st.h+
CONSENSUS/65%    ht+Gthpsu.cphss............tpW+sphhsAhppspchp.hp-tsp.ssspsh+
CONSENSUS/50%    pt+G+apsGsccsss............ssWKsphRCALppoc-FcplpDtSp.ssscsa+


IRF7_MOUSE/1-1   VYELSRE
CONSENSUS/80%    laplhs.
CONSENSUS/65%    laclhs.
CONSENSUS/50%    VYRLlPp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T