Consensus terms for the Int_alpha domain

ITA1_RAT/4-0     CGARFGTAIAA--VKDLNVD--GFND---VVIGAPLEDD----------------HAGAV
CONSENSUS/80%    ..shhG.sls...hhshp....t..s...lhhGAPh.....................Gtl
CONSENSUS/65%    .suhhGhuls...hs-hstc..uhsD...lllGAPhtt..................hGtl
CONSENSUS/50%    ssohFGaols...huDlssD..GhsD...llVGAPtsss................psGsV


ITA1_RAT/4-0     YIYHGSGK--TIREAYAQRIP
CONSENSUS/80%    hhh.........t........
CONSENSUS/65%    alh.......stphp.h.hht
CONSENSUS/50%    Ylhpspt...ussspstppls

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T