Consensus terms for the KR domain

FA12_BOVIN/1-8   ASCYDDRDRGLSYRGMAGTTLSGAPCQSWAS--EATYWNVTAEQVLNW---GLGDHAFCR
CONSENSUS/80%    tpCh.s..pG.tYcGphshT.sGh.C..Wst..st.h.........t......htcNaCR
CONSENSUS/65%    tpChts..sGpsYRGshspTtoGhtCptWssphschtph..stphssh.....hpcNYCR
CONSENSUS/50%    pcChsG..sGcsYRGTsusTpSGtsCQpWsuptPHp+ph.sssphPsts....LccNYCR


FA12_BOVIN/1-8   ---NPDN--DTRPWCFI-WKGDRLS-WNYCRLA-PCQA
CONSENSUS/80%    ...NPss..tttPWCas..hs.th..hphCtl...Ctt
CONSENSUS/65%    ...NPDu..pptPWCYT..tssphp.h-aCsl..pCps
CONSENSUS/50%    ...NPDGp.scuPWCYT..s-sslc.aEYCsls.pCss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T