Consensus terms for the MA3 domain

4826710/34-146   LEKKSKAIIEEYLHLN-DMKEAVQCV-QELASP--SLLFIFVRHGVESTLER---SAIAR
CONSENSUS/80%    hpp.h..hl.p.h....ph.cshppl..clt....t...thhhhhl..shpp....pt.t
CONSENSUS/65%    hccpht.llpphh..t.DhpEAhpsl.hcLphs..phptcllthllphshcc...tcphp
CONSENSUS/50%    l++clpsllcEYhpss.DssEAscsL.c-Lsls..ph+pEllcpllsssL-c...pcptc


4826710/34-146   EHMGQLLHQLL-CAGHLSTAQYYQGLYEILE-LAEDMEID---------------IPHVW
CONSENSUS/80%    phhs.lhpphh ..thh..ptht.uh..hhp..htch.hs..................hh
CONSENSUS/65%    chhuhLlpphh ptshhpspphppua.phhs.phpDltlD...............hPpth
CONSENSUS/50%    chhupLLpcLt ptshlsscshpcuFsclhc.slcDlslD...............lPcuh


4826710/34-146   LYLAELVTPILQEGGVP
CONSENSUS/80%    ..lsphhs.hl.tthls
CONSENSUS/65%    p.lupFluchltsshls
CONSENSUS/50%    phLupFlu+llsscsLs

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T