Consensus terms for the MADF domain

Q9VLA6/57-147    RFVNLVRTHKCLYDKK-VPEYRNRDNQEK------AWVLISKET------------RESV
CONSENSUS/80%    phlp.hppp.hlas.p...thtttt.ttt......hatpls.tht..............h
CONSENSUS/65%    pLIphlcppssLastp.p.papppphppp......sWppluppls..............s
CONSENSUS/50%    cLIctV+cpPsLW-pp.pssa+sppsccp......sWpcIupclshs............s


Q9VLA6/57-147    IHCKERWRNLR---ACLSRYIK----QQSGSEPQH----KPYYLT---EHMAFLLPFLK
CONSENSUS/80%    t.hhpphppl+...ppahpthp....................a....hpthtFlp.h.t
CONSENSUS/65%    ppspp+apsLR...spYp+phcphp.ttttt.........ttW...hhcphpFLpshhp
CONSENSUS/50%    cps+c+W+sLR...spYp+El++hp.spptst........spWp..aaccLpFLcshhp

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T