Consensus terms for the MHC_II_alpha domain

10141.ENSCPOP00000002210_from_HVSRY-AEFVQ-TQTPSGEY------MFELDEDEQFYVDLDKRQTVWRLPEFG---QAFA
CONSENSUS/80%    Hh....h.hhp.s.t.p.........h.thDt-p.a.sDhtppptl..ls.Fs....phs
CONSENSUS/65%    Hs..ahtthhp.shssssth......hapaDu-EhFasDhp+ccsVhpLPcFs....pas
CONSENSUS/50%    HV..ahsshap.shsPSGpa......sa-FDGDElFYVDlcK+ETVWpLPEFu....cFu


10141.ENSCPOP00000002210_from_-FDAQGGL----ANIAIMRTNLNFAIQDSNHTQAPS
CONSENSUS/80%    .ht.ptuh....hshths+..lphhhpt.pth...p
CONSENSUS/65%    thpspsul....tshshs+tsLshhhcpsstsss.s
CONSENSUS/50%    pF-sQuuL....sslAlsKsNLclllKpSNsTssss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T