Consensus terms for the MIF4G domain

YDF3_SCHPO/1-23  QRKVKGSLNKMT----LEKFDKISDQILEIAMQSRKEN-----DGRTLKQVIQLTFEKAT
CONSENSUS/80%    .thhpthhpcls.....t.hp..h.th.t...t..............ht.lhp.hhph..
CONSENSUS/65%    .cplpslhscls.....pthpphhpplhphhhp............thhptllphlhptsh
CONSENSUS/50%    p+plpulls+Ls....ssslcslhcpltphhhsp..........tptpppllctlhppst


YDF3_SCHPO/1-23  DEP-------NFSNMYARFARKMMDSIDDSIRDEGVLDKNNQPVRGGLLFRKYLLSRCQE
CONSENSUS/80%    ..........t.h.hhstlh.hht.h......................phht.hlphh.t
CONSENSUS/65%    tp........phhshhupLsshlptths....................phsphllpphhp
CONSENSUS/50%    tps.......shlssaApLsusLssphs....................cFsppLlsphpc


YDF3_SCHPO/1-23  DFERGWKANLPSGKAG----------------EAEIMSDEYYVAAAIKRRGLGLVRFIGE
CONSENSUS/80%    thpt.......................................p....tphht.hthhs.
CONSENSUS/65%    phpp.....................................t.pttphpphhshlpFlu-
CONSENSUS/50%    pFcp...................................hpppcpsspp+plssl+FluE


YDF3_SCHPO/1-23  LFKLSMLSEK-----IMHECIKRLLGNVTD-----------------------------P
CONSENSUS/80%    lh..thhp........hhthh..hh...................................
CONSENSUS/65%    Lhphphlptt......hhphlhthlt.hpp..............................
CONSENSUS/50%    Lashpllssp.....hlhssltpllpshsp..............................


YDF3_SCHPO/1-23  EEEEIESLCRLLMTVGVNID---------ATEKGHAAMDVYVLRMETITKIP--------
CONSENSUS/80%    ...tlthhh.hh..hG..h..................hpthh..hpthh...........
CONSENSUS/65%    ...plchlhthLppsGt.lt...........tpsppthpphhpthpphh.tt........
CONSENSUS/50%    p.pslcslsplLpssGppLp...........ppsspplcpllsplpshhpps........


YDF3_SCHPO/1-23  --------------------------NLPSRIKFMLMDVMDSRKNG
CONSENSUS/80%    ..............................phphhh..hh.hht.t
CONSENSUS/65%    ..........................phs.phchhlpphhplppsp
CONSENSUS/50%    ..........................phss+lcahlpslhpl+psc

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T