Consensus terms for the MIT domain

O60349/36-123    IREAYKKAFLFVNKGLNTDE---LGQKE-EAKNYYKQGIGHLLR--GISIS-SKESEHTG
CONSENSUS/80%    .t..hptAhp.lptuhp.-p....tpht.tAh.hYppuhphhhp..slth........pt
CONSENSUS/65%    hpshhppAhphlppAlpt-c...tspht.pAhphYpculchhhp..slpht..sstttpp
CONSENSUS/50%    pcsshscAt-hls+AlcsDc...susa-.cAlshYpcAl-hLlc..ulshc..ssscp+s


O60349/36-123    PGWESARQMQQKMKETLQNVRT-RLEI
CONSENSUS/80%    ..htphtphhp+hpph.t.h...p...
CONSENSUS/65%    shpt+sppahpRhcplpp.hpt.+.ts
CONSENSUS/50%    ul+sKspcYLcRAEcl+splps.+lss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T