Consensus terms for the Mre11_DNA_bind domain

222929.C5P693_from_289_to_466FKCEPIPLKTVRPFVMKEIVLSEEKEAQRLLRKE-----------NNRTEL-TRFLMGL-
CONSENSUS/80%    hphp.l.LpoVRsFhhcpl.Ltp........................tttl..thh.t..
CONSENSUS/65%    achp.IsLpTVRPFhhc-lsLtp.....tht..............pspppl.ppalppp.
CONSENSUS/50%    F+lcsIPL+TVRPFlh--lsLs-....hsls.s............ssppcl.pcaLppc.


222929.C5P693_from_289_to_466-----------VDE-LIEK----AKNDWL-------------------ASQDDFDGDESE
CONSENSUS/80%    ...........lpt.hlpp....up...................................
CONSENSUS/65%    ...........Vcp.hIpc....Aptph...............................p
CONSENSUS/50%    ...........V-p.hI-c....Acpphp..........................t..pp


222929.C5P693_from_289_to_466I-----------------------------------------------------------
CONSENSUS/80%    ............................................................
CONSENSUS/65%    ............................................................
CONSENSUS/50%    ............................................................


222929.C5P693_from_289_to_466------------------------------------------------------------
CONSENSUS/80%    ............................................................
CONSENSUS/65%    ............................................................
CONSENSUS/50%    ............................................................


222929.C5P693_from_289_to_466----------PLPLVRLRVDTSTPEGG----SFDCENPQRFSNRFVGRVANVNDVVQFHR
CONSENSUS/80%    ...........hPLlRL+lcao.........thp..Ns.RFuppa.spVANsp-hl.ah+
CONSENSUS/65%    ...........LPLIRL+V-Yos........shphhNspRFupcFss+VANspDllhFh+
CONSENSUS/50%    ..........pLPLIRLRV-You........sapshNspRFGp+FVG+VANPsDllpFaK


222929.C5P693_from_289_to_466KKKA-------TTA----ARGKT-DAPGETILSQLSSLDT--------------------
CONSENSUS/80%    ............t...............................................
CONSENSUS/65%    pp.........ppt..........t....t.....tt.......................
CONSENSUS/50%    ++t...pt...psptpt.ttht.ppthtpsthtpppsh......................


222929.C5P693_from_289_to_466-----VKVERLVRE----------FLT------AQSL----TILPQNSFGDAVSQF
CONSENSUS/80%    ......phpphltc..........hh.......t.pl....plL..tthspsltpa
CONSENSUS/65%    .....hplpsllpc..........hhp......ptpL....plLsppslscAlppF
CONSENSUS/50%    .....hcVEcLVs-..........ahs......pppL....slLscsulu-AlccF

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T