Consensus terms for the NIDO domain 

O08523/98-254    PFWADVH----NGIRGEIYYRE-----TMDPAILRRATKDIRKYFKDMT----------T
CONSENSUS/80%    .aht.hp........uthhapt.......p.hhl.hhhp.l...htt............t
CONSENSUS/65%    sFhsphc.......tGplaacp......pctthLppttptlpptassss..........t
CONSENSUS/50%    sFasclDh.....ssGclaYRE......s-sslLspuscsVppsFsssu..........s


O08523/98-254    FSATWVFIVTWEEVTFYGGSSTT----------PVNTFQAVLVS-----DGSYTFTLFNY
CONSENSUS/80%    apsp.shlhTW.pst.h.t...............hNTaQhhlhs.....stt.oas.F.Y
CONSENSUS/65%    FpsppshlsTW.pltshsst.............tsNTFQslLso.....ststTashFhY
CONSENSUS/50%    FcucpllllTWcsVsshsusps...........ssNTFQAlLuo.....DuupTYAlFlY


O08523/98-254    YEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLT------NFFSLPGSRTPEIVNIQETT
CONSENSUS/80%    .p.sht.................u.sGFssust..............sht..h..h...o
CONSENSUS/65%    tphshp..............ts.A.uGFssuss.............tstp.ph.pLtttS
CONSENSUS/50%    sshGhshtsstst.......pssApAGFsuGsus........h.hssusppsspsLspsS


O08523/98-254    NV--NVPGRWAFKVDGKEI
CONSENSUS/80%    s...th.Ghahaclst..h
CONSENSUS/65%    Ns..shsGhWha+lsthth
CONSENSUS/50%    Nl..GlPGpWlFRlcsscl

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T