Consensus terms for the NOSIC domain

399550.Smar_1256_from_142_to_1LAVQAIRAIDD-----IDKTINLYVARLREWYSLHFPELDELV-REHSDYARIVYELGH
CONSENSUS/80%    hllps.thh.p.....l-ppls.h..hl+-hYuh+FPELtpll..p...Yhphl..htp
CONSENSUS/65%    hIlpulshl-p.....lDc-lNhhthRlREWYuh+FPELspll..cshpYscllthlss
CONSENSUS/50%    hIlQAlsLLD-.....lDK-lNpastRlREWYuhHFPELs+lV.s-shpYs+lVptlGs

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T