Consensus terms for the PA14 domain

Q8PLM2/307-446   KAGALTARYAINGKHILERRESE-----------VNYQYLSDLTKYPKKAITKDKNSRMQ
CONSENSUS/80%    .t.Gh.ht.h.tt......................t....................tphs
CONSENSUS/65%    spsGl.hthahpptth.s................hpssth.sh.htst..sts.ttsphs
CONSENSUS/50%    sssGl.tshYtsssshssh.hh............hsssshsssttsspssspstssscau


Q8PLM2/307-446   VTWEGEIEALTGGEHTF--SLY------SSEYAKLY------VDGKLVVDRW---RQNW-
CONSENSUS/80%    h.hpuhhhs..sGta.h...h.......ssss.thh......lssp.hlsp.........
CONSENSUS/65%    spasGhlpsspsGpYpF..tlt......ucsssplh......lsuphll-pt...s.t..
CONSENSUS/50%    lcasGplpsspoGsYsF..pls......uDcus+La......lDGchllDss...sppt.


Q8PLM2/307-446   ------------------NPWNHEFKLDLEPGQRHTVKVEWDLIDPSYI---------AL
CONSENSUS/80%    ........................tth.h.tutha.lcl.h.tt...............h
CONSENSUS/65%    .....................phptslthhsuphapl+lcahpttssth.........pl
CONSENSUS/50%    ...................ttsppsslsLpuGpsYsl+lEYtcpssssth........pL


Q8PLM2/307-446   LHRDPLPAAEAKDLS
CONSENSUS/80%    .h..st..t......
CONSENSUS/65%    tat.sshtttthstt
CONSENSUS/50%    sWssssssppsssps

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T