Consensus terms for the PDZ domain

AF017106_1/1-8   IHVTILHKEEG------------AGLGFSLAGGADLEN---------------------K
CONSENSUS/80%    ....h.h.p......   .......hGhtl.t............................
CONSENSUS/65%    t.hhlplt+t.....   .....tshGhpltstt.........................t
CONSENSUS/50%    phpplplp+ss....   .....ssLGlslsuspst.......................p


AF017106_1/1-8   VITVHKVFPN--------GLASQEGT-------------------IQKGNEVLSING---
CONSENSUS/80%    .hhlttl..s........usAttss....................lp.GD.lhtlss...
CONSENSUS/65%    slhlpplh.s........usAtpsG....................lp.GDhIlplNG...
CONSENSUS/50%    ulhlsslhsG........usAscsG....................LcsGDpIlpVNG...


AF017106_1/1-8   ----KSLK---GTTHNDALAILRQAREP----RQAVIVTRK-
CONSENSUS/80%    ......h....tht..thh.hhtt.........ltlhl.p..
CONSENSUS/65%    ....hslp...shsptpshthlpps.......plplhlhctt
CONSENSUS/50%    ....pslp...shscpcslphl+sst......plsLplpRss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T