Consensus terms for the PI3K_C2 domain 

PI3K_ARATH       FRIEKLD-GNLPVK-----KSSDAGVVSIAEEKKP-------ELYIECALYID-------
CONSENSUS/80%    h.h.tl..ht...........h.hhhpt....hpt.......phhlphtlhtt.......
CONSENSUS/65%    hphtsLp.hsp.h........phhhhpth.hphpp.h.....plalphplaps.......
CONSENSUS/50%    hplssLppsscsht......hphtslcslhlshsssh.....claVpssLaaG.......


PI3K_ARATH       GAPFGLPMRTRL-------KTTGPP-----YCWNELITL-SSKYRDLTAHSQLAITVWDV
CONSENSUS/80%    sp.hs..h.op.........sh..........Wsphl.h.slthpplshtshlshslhth
CONSENSUS/65%    sc.hspslpos........hsht.p.....hpWschlph.slphssLPptuhLslslash
CONSENSUS/50%    ucslssslsToh.......tshpsc.....hsWN-alsa.sIplscLPRsApLslolass


PI3K_ARATH       SC-GKTEGLIG------GATVLLF
CONSENSUS/80%    ......t...........tt.t.h
CONSENSUS/65%    ht.sttth........ttsphs.h
CONSENSUS/50%    ps.spsss........sssshsht

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T