Consensus terms for the PI3K_p85B domain

P11A_HUMAN       IVTLECLREATLVTIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLC
CONSENSUS/80%    hhplcs..t.pl..hK..hhp.ht.h.hh.h..c.ppY.hhtls..h.hE.h.s-sp.Ls
CONSENSUS/65%    llpLcsshEsTlssIKppLacps+phPhtpllh-.ssYhFhslsppuphE.hhDET+RLs
CONSENSUS/50%    LlsLEVsREATISsIKHELFKQA+sMPLGsLLpDssSYlFsuVNQTAEIEElFDETRRLC


P11A_HUMAN       DLRLF--QPFLKVIEPVGNR
CONSENSUS/80%    clp.a...shL.lhp.ss..
CONSENSUS/65%    -lc.a..hPhLpLhp.ssss
CONSENSUS/50%    DLRLF..FPlLKLlEPoGss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T