Consensus terms for the PINc domain

O07635/3-135     KIYVLDTNVLLQDP--------------------NAIFSFEE---------NEVVIPAVV
CONSENSUS/80%    hhhhhDoshhh..h....................thh..............h.hhhs..s
CONSENSUS/65%    hthllDTshlltth....................phhpph.p........thphhls.hV
CONSENSUS/50%    tplVlDTNlllpsh...................hcslcpltp.......tptclllsssV


O07635/3-135     LEEVDSKKR----------YMDEVGRNARHVSKLIDALRQ--KGRLHEHVPLDTGG----
CONSENSUS/80%    hpEl..hh..........................h..h......th......t.......
CONSENSUS/65%    lpElptht.......................hphhpphtt...tphthhhhhp.......
CONSENSUS/50%    lsELcpht....................htthpplcclsp...tctthphhtsp......


O07635/3-135     -------------TLRIELNHRSFHQLQEIF--------IEKTNDNRILAVAKNLSLEEE
CONSENSUS/80%    ..................ht........................Dthhhthsh.h.....
CONSENSUS/65%    ..................hpt..htt.................tDthlhthshpht....
CONSENSUS/50%    .............hh.pplcppsspstt...............sDshllssApphp....


O07635/3-135     T----------KENGRPVILVSKDVLVRV
CONSENSUS/80%    ..................hlho.D.t.t.
CONSENSUS/65%    ................thhlhTtDpshpp
CONSENSUS/50%    ................sslLlTsDcsh+c

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T