Consensus terms for the PKD domain

Q50247/1-79      LSRFSASPTSGK-----APLTVSFTDQS--------------TGAPAAWRW---------
CONSENSUS/80%    .h.h..t..............h.hps...  ...............hth.W.........
CONSENSUS/65%    ssthssssst........s.slpapsps.  ...........sst.hsapW.........
CONSENSUS/50%    sushsssssssh.....sspsVsFssss.  ...........sGsslsapW.........


Q50247/1-79      -TF-GDG-----------------------SGSRE----KNPVHTYNES----------G
CONSENSUS/80%    .sh.sst...........................t.....t.shta.ps..........G
CONSENSUS/65%    .sh.GDu.......................pstpt....tsssasasps..........G
CONSENSUS/50%    .sF.GDG.......................ssssu....sssoHoYscs..........G


Q50247/1-79      QYTVTLTASNANG-----------------------------------------SNALTK
CONSENSUS/80%    .aphplts.st............................................sp..h
CONSENSUS/65%    pYslplsspssss.........................................ssstsh
CONSENSUS/50%    sYsVsLolssssG.........................................osotos


Q50247/1-79      SRYIVVS
CONSENSUS/80%    .h.l...
CONSENSUS/65%    plhltss
CONSENSUS/50%    slpVsss

The grouping of amino acids to classes and class abbreviation (the key) used within consensus sequences are shown below:

ClassKeyResidues
alcoholoS,T
aliphaticlI,L,V
any.A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y
aromaticaF,H,W,Y
chargedcD,E,H,K,R
hydrophobichA,C,F,G,H,I,K,L,M,R,T,V,W,Y
negative-D,E
polarpC,D,E,H,K,N,Q,R,S,T
positive+H,K,R
smallsA,C,D,G,N,P,S,T,V
tinyuA,G,S
turnliketA,C,D,E,G,H,K,N,Q,R,S,T